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Yohimbine Hydrochloride
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Product Name Yohimbine Hydrochloride
Price: $18 / 20mg
Catalog No.: CN02197
CAS No.: 65-19-0
Molecular Formula: C21H26N2O3 HCL
Molecular Weight: 390.91 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: White powder
Source: The peels of Corynante Yohimbe.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
SMILES: COC(=O)[C@H]1[C@@H](O)CC[C@@H]2[C@@H]1C[C@@H]1N(C2)CCc2c1[nH]c1c2cccc1.Cl
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Description Yohimbine hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.IC50 value:Target:In vitro:In vivo: Yohimbine hydrochloride (0.2 mg/kg, i.p.) was administered to rats 1h before the stress session daily for 14 consecutive days and its effect was assessed. Results of this section revealed that, immersion of rats in cold water significantly decreased sexual arousal and motivation as indicated by increased latencies and intervals. Decreased copulatory activity was confirmed by decreased testosterone, luteinizing hormone (LH) and follicle-stimulating-hormone (FSH) levels as well as decreased cholesterol content in rat testes. Treatment with yohimbine significantly increased the sexual arousal and potency and corrected the effects induced by stress on the mating behavior of male rats [1].
Boiling Point542.979ºC at 760 mmHg
Flash Point282.184ºC
Exact Mass390.171021
PSA65.56000
LogP3.38700
Storage condition2~8°C